Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: Bis(norbornadiene)rhodium (I) tetrafluoroborate, is researched, Molecular C14H8BF4Rh, CAS is 36620-11-8, about Scalable Asymmetric Synthesis of MK-8998, a T-type Calcium Channel Antagonist.Product Details of 36620-11-8.
Two scalable and efficient synthetic routes for the synthesis of a T-type calcium channel antagonist MK-8998 were developed from a simple pyridine building block. The key step to set the stereochem. relied on either chiral rhodium catalyst-mediated asym. hydrogenation of an enamide or transamination of an arylketone that provided the corresponding product in high enantioselectivity and high yield.
When you point to this article, it is believed that you are also very interested in this compound(36620-11-8)Product Details of 36620-11-8 and due to space limitations, I can only present the most important information.
Reference:
Quinuclidine – Wikipedia,
Quinuclidine | C7H13N | ChemSpider