Black, Jacob W. published the artcileAn Optical Tweezers Platform for Single Molecule Force Spectroscopy in Organic Solvents, Application of Dbco-acid, the publication is Nano Letters (2017), 17(11), 6598-6605, database is CAplus and MEDLINE.
Observation at the single mol. level was a revolutionary tool for mol. biophysics and materials science, but single mol. studies of solution-phase chem. are less widespread. The authors develop an exptl. platform for solution-phase single mol. force spectroscopy in organic solvents. This optical-tweezer-based platform was designed for broad chem. applicability and uses optically trapped core-shell microspheres, synthetic polymer tethers, and click chem. linkages formed in situ. Stable optical trapping of the core-shell microspheres in 10 different solvents was observed, as was single mol. link formation in 4 different solvents. These experiments demonstrate how to use optical tweezers for single mol. force application in the study of solution-phase chem.
Nano Letters published new progress about 1353016-70-2. 1353016-70-2 belongs to quinuclidine, auxiliary class Other Aromatic Heterocyclic,Carboxylic acid,Amide,Inhibitor,Inhibitor, name is Dbco-acid, and the molecular formula is C19H15NO3, Application of Dbco-acid.
Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider