Duan, Wen-Long published the artcileStructures, kinetic and synergistic mechanisms studies of urease inhibition of copper(II) complex based on MOSs, Related Products of quinuclidine, the publication is Journal of Molecular Structure (2020), 127958, database is CAplus.
Urea can undergo fast enzymic hydrolysis catalyzed by urease, generating a variety of N species that can cause environment damage. Therefore, urea hydrolysis can be reduced by adding urease inhibitors. Heterocyclic compound, 4,4′-methylenebis (N-(pyridine-2-lmethyl)cyclohexanamine) (L) was used to react with MCl2(M = Zn, Cu, Co, Cd), producing a series of metal-organic salts [H4L]4+·2 [XCl4]2- [X = Zn (1), Cu (2), Co (3), Cd (4)]. The salt 2 has an obvious inhibitory effect on the inhibitory activity against jack bean urease, with the IC50 of 2 being 0.34 ± 0.01μΜ (0.5 h) and 0.93 ± 0.01μM (3 h). Mol. docking was used to study the inhibition mechanism, which indicates that copper complex can be used as a urease inhibitor, and the salt 2 can reduce relevant nitrogen loss.
Journal of Molecular Structure published new progress about 1761-71-3. 1761-71-3 belongs to quinuclidine, auxiliary class Ploymers, name is 4,4-Diaminodicyclohexyl methane, and the molecular formula is C13H26N2, Related Products of quinuclidine.
Referemce:
https://en.wikipedia.org/wiki/Quinuclidine,
Quinuclidine | C7H13N | ChemSpider